Failure Science has failed us. We still don’t know much about anything, despite having so much data/information.
Addiction The definition of addiction: you think about the next hit, while you still haven’t finished the current one.
Success There’s no such thing as a “successful life”, since every life ends up with death, thus, ultimately, being unsuccessful.
Nature Nature is like a blind painter: it keeps churning up species, without knowing which one will succeed. If it sticks, it sticks.